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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF7 All Species: 38.79
Human Site: S349 Identified Species: 85.33
UniProt: Q8N684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N684 NP_001129512.1 471 52050 S349 K R N R A I S S S A I S K A V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082435 519 57231 S397 K R N R A I S S S A I S K A V
Dog Lupus familis XP_533274 514 56498 S392 K R N R A I S S S A I S K A V
Cat Felis silvestris
Mouse Mus musculus Q8BTV2 471 51993 S349 K R N R A I S S S A I S K A V
Rat Rattus norvegicus Q5XI29 462 51054 S340 K R N R A I S S S A I S K A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL34 551 59341 S426 N R N R A I S S S A I S R A V
Frog Xenopus laevis Q6DDW4 548 59387 S422 N R N R A I S S S A I S R A V
Zebra Danio Brachydanio rerio Q6NWC6 545 58757 S419 N R N R A I S S S A I S R A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSH4 652 71076 S460 S R N R T V S S S A I A R A V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_501551 489 53643 M380 D A E F E D V M T R N Q T V S
Sea Urchin Strong. purpuratus XP_782654 898 96357 S759 N R N R N V S S S A I A R A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 89.4 N.A. 98.7 96.5 N.A. N.A. 44.2 43.9 44.5 N.A. 34.8 N.A. 31.2 21.8
Protein Similarity: 100 N.A. 84.3 89.8 N.A. 99.3 97.2 N.A. N.A. 56.8 56.2 58.1 N.A. 46.1 N.A. 47.4 34.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 86.6 86.6 86.6 N.A. 66.6 N.A. 0 66.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 93.3 N.A. 86.6 N.A. 6.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 73 0 0 0 0 91 0 19 0 91 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 73 0 0 0 0 91 0 0 0 0 % I
% Lys: 46 0 0 0 0 0 0 0 0 0 0 0 46 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 37 0 91 0 10 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 91 0 91 0 0 0 0 0 10 0 0 46 0 0 % R
% Ser: 10 0 0 0 0 0 91 91 91 0 0 73 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 0 10 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 19 10 0 0 0 0 0 0 10 91 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _